Gurugram, June 21: A three-and-half-year-old girl from Odisha was cured from an incompatible kidney transplant. She was suffering from a rare kind of renal failure.
Doctors claim to be first-ever surgery on such a small patient in entire south Asia. The entire process of surgery cost Rs 24 lakh.
Pratyasha was diagnosed with Reflex Nephropathy when she was just a month old and could not pass urine which caused renal problems and later failure.
The doctors at th Medanta – The Medicity had only one solution to save her life was kidney transplant. However, there were no blood group-compatible donors.
After six months of desperate search, the Kidney and Urology Institute of the hospital planned to take the mother as the donor with A+ blood group while the child was B+, involved the biggest risk of hyper-acute rejection.
“We did not have a compatible donor, so we had to go for the incompatible kidney transplant. Dialysis on the three-year-old was not easy. After developing a proper plan, we reduced the antibody cells. We used a drug called Rituximab. Nowadays, we have a method called immunoadsorption to remove the anti-bodies,” said Siddharth Sethi, Consultant, Pediatric Nephrology at Medanta.
Prasun Ghosh, Associate Director – Renal Transplantation, at Medanta hospital, said Pratyasha weighed only 10 kg, put her to additional risk of rejection and also surgical complications due to smaller size of the child.
Her abdomen was small, hence putting an adult-sized kidney into a small abdomen was technically challenging.
“There was also a high risk of clotting in blood vessels, when small vessels of the child are joined to the donor’s kidney.” However, everything goes well.
Doctors said she would have to be under medication worth Rs 12,000-13,000 every month.