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Vegetarian diet may up cancer, heart disease risk in Indians: Study

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Vegetarian diet
Scientists found evidence that a vegetarian diet has led to a mutation that may make people more susceptible to inflammation, and by association, increased risk of heart disease and colon cancer.
Vegetarian diet has led to a mutation that may make people more susceptible to inflammation, increased risk of heart disease and colon cancer.

Long term vegetarian diet can lead to a genetic mutation that may increase the risk of cancer and heart disease in Indians, a new study by Cornell University researchers has claimed.

Scientists found evidence that a vegetarian diet has led to a mutation that may make people more susceptible to inflammation, and by association, increased risk of heart disease and colon cancer.

broccoli-mainThe discovery by researchers including Kumar Kothapalli from Cornell University in US provides the first evolutionary detective work that traces a higher frequency of a particular mutation to a primarily vegetarian population from Pune (about 70 per cent), when compared to a traditional meat-eating American population, made up of mostly Kansans (less than 20 per cent).

By using reference data from the 1000 Genomes Project, researchers provided evolutionary evidence that the vegetarian diet, over many generations, may have driven the higher frequency of a mutation in the Indian population.

The mutation, called rs66698963 and found in the FADS2 gene, is an insertion or deletion of a sequence of DNA that regulates the expression of two genes, FADS1 and FADS2. These genes are key to making long chain polyunsaturated fats, researchers said.

Among these, arachidonic acid is a key target of the pharmaceutical industry because it is a central culprit for those at risk for heart disease, colon cancer, and many other inflammation-related conditions, they said.

Treating individuals according to whether they carry 0, 1, or 2 copies of the insertion, and their influence on fatty acid metabolites, can be an important consideration for precision medicine and nutrition.

The insertion mutation may be favoured in populations subsisting primarily on vegetarian diets and possibly populations having limited access to diets rich in polyunsaturated fats, especially fatty fish, researchers said.

“With little animal food in the diet, the long chain polyunsaturated fatty acids must be made metabolically from plant PUFA precursors,” researchers said.

“The physiological demand for arachidonic acid, as well as omega-3 EPA and DHA, in vegetarians is likely to have favoured genetics that support efficient synthesis of these key metabolites,” they said.

Changes in the dietary omega-6 to omega-3 balance may contribute to the increase in chronic disease seen in some
developing countries, researchers said.

The findings were published in the journal Molecular Biology and Evolution.

Cities

20 new containment zones formed in Delhi; 122 total

Covid cases in the national capital crossed the 18,000 mark on Saturday.

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covid lockdown delhi

New Delhi, May 30 : The number of Containment Zones in the national capital rose to 122 on Saturday with 20 new being formed in the last 24 hours, according to Delhi Government.

Among the 20 new containment zones, one is in East, three in North, three in south-east and 13 in West zone.

The highest 24 containment zones are in the North district. The South East has 17 containment zones while the South district has 12 zones.

Among those having the least zones is the New Delhi district with three zones.

The South West has 12 such zones while the North West districts has 13 containment zones.

The Central district has seven zones and the North East district has four zones while Shahdara district has eight zones.

Six containment zones are in the East district.

So far, total 53 zones have been de-contained, as per the data shared by the Delhi government on Saturday — the highest 12 from the West district. On Saturday, three zones were freed — two in the south-east district and one in the South district.

Covid cases in the national capital crossed the 18,000 mark on Saturday.

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Gujarat’s corona death toll now 1,007, total cases 16,356

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Coronavirus Death US

Gandhinagar, May 30 : Gujarat’s death toll due to novel coronavirus climbed to 1,007 on Saturday as 27 more persons succumbed to the dreaded virus. With 412 new cases, the total crossed the 16K-mark to 16,356.

The state has 6,119 active cases at present, of which the condition of 6,057 is stable. The condition of 62 patients is critical and are on ventilators.

The state has been registering over 20 deaths daily since beginning of May. Of the 27 new casualties, Ahmedabad reported 24. A patient each from Gandhinagar, Banaskantha and Mahesana also succumbed to the virus on Saturday.

A total of 621 patients were discharged on Saturday, taking the total cured patients to 9,230.

According to the state government, the recovery rate of Gujarat has now improved to 56.43% from 39.20% 15 days back.

A total of 793 persons have succumbed to the virus in May till date. Out of the total deaths, 822 deaths were reported in Ahmedabad (81.62%), followed by 67 in Surat, 39 in Vadodara, 14 in Gandhinagar, 10 in Anand, 8 in Bhavnagar, and 6 in Panchmahals.

Of 412 new cases, Ahmedabad had the maximum 284, followed by Surat 55, Vadodara 28, Gandhinagar 12, Aravalli 6, Banaskantha, Rajkot, Sabarkantha and Panchmahals 3 each, Anand, Patan, Jamnagar and Chotta Udepur 2 each, and Bhavnagar, Kutch, Mahisagar, Amreli, Porbandar and other states one positive case each.

Out of Gujarat’s total 16,356 cases, Ahmedabad leads with maximum 11,881, followed by Surat 1,565, Vadodara 1,009, Gandhinagar 261, Bhavnagar 120, Mahisagar 115, Mahesana 112, Rajkot 108, Banaskantha 107, Aravalli 103, Sabarkantha 101, Anand 99, Panchmahals 85, Patan 78, Kutch 80, Kheda 65, Botad 59, and Jamnagar 54 cases.

Health authorities have so far carried out 2,05,780 tests in the state, of which 16,356 tested positive and 1,89,424 negative.

People quarantined total 2,53,845, out of which 2,45,701 are home quarantined and 8,144 in institutional quarantine.

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Cities

Kejriwal assures his govt is way ahead in Covid planning

Kejriwal also informed that while the cases have doubled in the last 15 days, only 2,100 are in hospitals and rest are undergoing treatment at their homes.

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Arvind Kejriwal

New Delhi, May 30 : Delhi Chief Minister Arvind Kejriwal on Saturday said while the coronavirus cases are increasing, the government is ahead of the infection in terms of preparations.

Kejriwal said so far, 398 people have died due to the infection.

“In the past few days, the cases have been increasing and I assure that we are ahead in planning. We have made arrangements even more than what is required. We cannot have a permanent lockdown to fight against coronavirus,” he said.

Kejriwal, while addressing the media, also said that the aim is that there are sufficient beds and arrangements in the hospitals to deal with the cases and fewer deaths taking place.

“We have procured a large number of beds to treat Corona(virus) patients. Though the number of cases are rising, we have sufficient arrangements to treat them,” he added. He informed that last week the city had 4,500 beds for covid treatment.

“In the past week, we made arrangements for 2,100 more beds. We now have about 6,500 beds. By June 5, we will have 9,500 beds. We are taking over hospitals and hotels,” he added.

Kejriwal also informed that while the cases have doubled in the last 15 days, only 2,100 are in hospitals and rest are undergoing treatment at their homes.

“Today, 17,386 cases are there and only 2,100 patients are in hospitals, only about 600 more people have been admitted to the hospitals in the last 15 days,” he added.

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