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Three cups of filtered coffee may protect you from diabetes

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diabetes

London: In a good news for coffee lovers, researchers have found that coffee can help reduce the risk of developing type 2 diabetes – but only filtered coffee, rather than boiled coffee.

The study, published in the Journal of Internal Medicine, shows that the choice of preparation method influences the health effects of coffee.

The findings from Chalmers University of Technology and Umea University in Sweden, offer new insight into this connection, using a novel method to help differentiate between the effects of filtered coffee and boiled coffee.

“We have identified specific molecules – ‘biomarkers’ – in the blood of those taking part in the study, which indicate the intake of different sorts of coffee. These biomarkers are then used for analysis when calculating type 2 diabetes risk,” said study researcher Rikard Landberg, Professor at Umea University.

“Our results now clearly show that filtered coffee has a positive effect in terms of reducing the risk of developing type 2 diabetes. But boiled coffee does not have this effect,” Landberg added.

With the use of these biomarkers, the researchers were able to show that people who drank two to three cups of filtered coffee a day had a 60 per cent lower risk of developing type 2 diabetes than people who drank less than one cup of filtered coffee a day.

Consumption of boiled coffee had no effect on the diabetes risk in the study.

To differentiate the diabetes risk for boiled and filtered coffee, a new technique called metabolomics was used, in combination with classic dietary questionnaires.

Metabolomics makes it possible to identify the blood concentration of specific molecules from a given food or drink and use that as an objective measurement of intake – instead of simply relying on self-reported intakes from the questionnaires, which are prone to large errors.

“Metabolomics is a fantastic tool, not just for capturing the intake of specific foods and drinks, but also for studying the effects that that intake has on people’s metabolism. We can derive important information on the mechanisms behind how certain foods influence disease risk,” said study lead author Lin Shi.

According to the researchers, many people wrongly believe that coffee has only negative effects on health.

This could be because previous studies have shown that boiled coffee increases the risk of heart and vascular diseases, due to the presence of diterpenes, a type of molecule found in boiled coffee.

“But it has been shown that when you filter coffee, the diterpenes are captured in the filter. As a result, you get the health benefits of the many other molecules present, such as different phenolic substances. In moderate amounts, caffeine also has positive health effects,” Landber said.

Many other types of coffee preparation were not specifically investigated in the study, such as instant, espresso, cafetiere, and percolator coffee.

The study stresses that the health impacts of coffee do not depend solely on if it is filtered or not. They also vary with how the coffee beans, and the drink in general, are managed.

Disaster

Novavax begins clinical trial of Covid-19 vaccine in Australia

US biotech firm Novavax begins Covid-19 vaccine trials on Australian volunteers after getting $388mn from Bill Gates-backed fund

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Bill Gates Covid Vaccine

Sydney, May 26 : US-based biotechnology company Novavax is testing a new coronavirus vaccine on human subjects for the first time, launching a phase one clinical trial with a massive grant from an agency founded by Bill Gates, kicking off a storm of concerns online.

Preliminary immunogenicity and safety results from the Phase 1 portion of the trial are expected in July 2020, Novavax said on Monday.

“Administering our vaccine in the first participants of this clinical trial is a significant achievement, bringing us one step closer toward addressing the fundamental need for a vaccine in the fight against the global Covid-19 pandemic,” said Stanley Erck, President and Chief Executive Officer of Novavax.

“We look forward to sharing the clinical results in July and, if promising, quickly initiating the Phase 2 portion of the trial.”

The Phase 1/2 clinical trial is being conducted in two parts. The Phase 1 portion of the trial is enrolling approximately 130 healthy participants 18 to 59 years of age at two sites in Australia.

The Phase 2 portion is expected to be conducted in multiple countries, including the US, and would assess immunity, safety and Covid19 disease reduction in a broader age range.

The trial is being supported by the recently announced funding arrangement with the Coalition for Epidemic Preparedness Innovations (CEPI), an innovative partnership between public, private, philanthropic, and civil society organizations, launched at Davos in 2017, to develop vaccines to stop future epidemics.

NVX-CoV2373 includes Novavax’ proprietary Matrix-M adjuvant to enhance immune responses and stimulate high levels of neutralising antibodies.

Novavax said it identified NVX-CoV2373 as its lead SARS-CoV-2 candidate following pre-clinical testing that demonstrated high immunogenicity and high levels of neutralising antibodies.

The availability of a safe and effective vaccine for COVID-19 is well-recognised as a key tool to control the pandemic. At the same time, the efforts needed to rapidly develop, evaluate and produce this at scale are enormous.

According to the WHO, it is important to evaluate as many vaccines as possible as we cannot predict how many will turn out to be viable.

To increase the chances of success, it is critical to test all candidate vaccines until they fail, the WHO said, adding that it is working to ensure that all of them have the chance of being tested at the initial stage of development.

Over 120 vaccines have been proposed across the world including in India.

There are currently several vaccines in clinical evaluation, and about 70 in pre-clinical evaluation.

India’s Union Health Minister Harsh Vardhan on Sunday said that at least four of the 14 candidate vaccines for novel coronavirus in the country may enter the clinical trial stage very soon.

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Health

BJP states concealing Covid-19 data, says Maharashtra Congress

Taking a swipe at Leader of Opposition Devendra Fadnavis, the Congress leader advised his BJP to “first look at the failed Gujarat model” before criticising this state.

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Sachin Sawant

Mumbai, May 26 : In a blistering counter-attack, the Congress’ Maharashtra unit on Tuesday alleged that Bharatiya Janata Party-ruled states like Gujarat are suppressing Covid-19 data and indulging in politics during the ongoing pandemic.

While Gujarat is not conducting enough Covid-19 tests, all BJP-administered states in the country are concealing the real coronavirus data, state party Spokesperson and General Secretary Sachin Sawant claimed.

“The Gujarat High Court has lambasted the Gujarat healthcare system terming the hospitals there as worse than dungeons and compared the situation to a sinking ship like ‘Titanic’. The situation is near-identical in Uttar Pradesh and Madhya Pradesh,” Sawant told media persons.

Taking a swipe at Leader of Opposition Devendra Fadnavis, the Congress leader advised his BJP to “first look at the failed Gujarat model” before criticising this state.

He pointed out that the Gujarat HC had taken suo moto cognizance of a doctor’s complaint and come down heavily on the Gujarat healthcare system which is paralysed, exposing the inefficiency of the BJP government there.

Adding to this was the state Advocate-General’s submission to the court that “more tests may lead to 70 per cent of the population testing Covid-19 positive, thereby creating a fear psychosis among the people”.

With the current population of Ahmedabad estimated to be 78 lakh, and with 70 per cent potentially Covid-19 positive, there could be a minimum 40 lakh patients only in that city, Sawant said, adding the BJP has no right to criticise the Maharashtra government.

“In Maharashtra, the government is working scientifically, not indulging in clapping, lighting lamps or clanging plates. The situation is tough now, but when the Opposition points it out, the government takes suitable steps. Corona is the enemy of humanity, but the power-hungry BJP leaders in the state and Centre consider the state government as its enemy,” said Sawant sharply.

Against this, he recalled how the entire state including the (then) Opposition Congress-Nationalist Congress Party stood by Fadnavis when he was the state CM, though his party president Chandrakant Patil made irresponsible statements then.

In the same vein, Sawant urged the BJP leaders including Fadnavis, Narayan Rane and Subramaniam Swamy to cooperate with the Maha Vikas Aghadi government, arrange for funds to be released from the Centre, more trains for migrants and other forms of assistance in public interest.

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Cities

Delhi govt orders 28 ventilators, 435 oxygen concentrators

Delhi has 19 COVID Care Centres (CCC) with 5,716-bed capacity. The state has 50,000 PPEs in stock.

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ventilator, prototype

New Delhi, May 26 : Amid rising coronavirus cases, the Delhi Health Department has placed orders for 30,000 PPE kits, 3.5 lakh N-95 masks, 28 ventilators and 435 oxygen concentrators, according to a statement by the Raj Niwas, here on Tuesday.

The Secretary (Health) also presented the ‘situational analysis of Covid-19 in Delhi’ to Lieutenant Governor Anil Baijal.

Up to May 25, there were 14,053 confirmed cases in Delhi. Of this, 6,771 patients recovered or migrated. The case fatality rate in Delhi is 1.96 per cent against the national average of 2.57 per cent.

As on May 25, the Lt Governor was informed, 34 labs were functional for Covid-19 tests. Till date, 1,74,469 cumulative tests had been conducted with the positivity rate as on May 25 being 8.06 per cent.

Adequate supply of medical essentials has been ensured and more ventilators are being procured. At present, 4,462 beds, 429 ICUs, 343 ventilators and 2,632 oxygen supported beds are available in the Covid hospitals.

Delhi has 19 COVID Care Centres (CCC) with 5,716-bed capacity. The state has 50,000 PPEs in stock.

The Secretary also informed Baijal about augmentation of the bed capacity by 25 per cent in private hospitals with 50 plus beds, earmarking of 20 per cent beds for Covid patients in these hospitals, daily health monitoring of the home isolated Covid patients and raising isolation beds in the CCCs.

The Lt. Governor asked the Health Department to review medical infrastructure capacity building and remove bottlenecks immediately. The trend of the past 10-15 days should be analysed for future management, Baijal said and advised monitoring of containment zones on a dynamic basis for focused action.

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