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Serum Institute to manufacture 200mn doses of Covid-19 vaccine

As a part of the expanded agreement, Serum Institute will also manufacture the antigen component of NVX‑CoV2373, Novavax’s Covid‑19 vaccine candidate
US-based Novavax’s vaccine is in mid-stage trials after an early-stage trial showed it produced high levels of antibodies against the novel coronavirus

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Covid 19 Vaccine

New Delhi, Sep 29 : A further collaboration among the Serum Institute of India (SII), the world’s largest vaccine manufacturer by volume, Gavi and the Bill and Melinda Gates Foundation will accelerate the manufacture and delivery of up to 100 million doses of safe and effective Covid-19 vaccines for India and low-and middle income countries.

In August, Novavax signed a deal with Pune-based Serum Institute to produce a minimum of one billion doses of its vaccine candidate for low-and middle-income countries and India.

However, as a part of the expanded agreement, Serum Institute will also manufacture the antigen component of NVX‑CoV2373, Novavax’ COVID‑19 vaccine candidate.

“Today’s agreement with Serum Institute enhances Novavax’ commitment to equitable global delivery of our COVID-19 vaccine. With this arrangement, we have now put in place a global supply chain that includes the recently acquired Praha Vaccines and partnerships with leading biologics manufacturers, enabling production on three continents,” said Stanley C. Erck, President and Chief Executive Officer of Novavax.

“We continue to work with extraordinary urgency to develop our vaccine, now in Phase 2 clinical trials, and for which we anticipate starting Phase 3 efficacy trials around the world in the coming weeks,” the company said in a statement.

US-based Novavax’s vaccine is in mid-stage trials after an early-stage trial showed it produced high levels of antibodies against the novel coronavirus.

Serum is the world’s largest vaccine manufacturer by number of doses produced and sold globally (more than 1.3 billion doses). It is estimated that about 65% of the children in the world receive at least one vaccine manufactured by Serum Institute. Vaccines manufactured by Serum are accredited by the World Health Organization, Geneva and are being used in approximately 170 countries across the globe.

Moreover, the Indian Council of Medical Research (ICMR) and SII have also partnered for clinical development of a glycoprotein subunit nanoparticle adjuvanted vaccine developed by Novavax.

The trial will be initiated in the second half of October after the vaccine is manufactured by SII. The trial is led by ICMR-National AIDS Research Institute (NARI), Pune.

Meanwhile, at a Union Health Ministry briefing on the prevailing Covid-19 situation in the country, an ICMR official said three vaccines are at the clinical trial stage in India.

“Cadila and Bharat Biotech have completed phase-I trials. Serum Institute has completed phase II-B3 trials, and will start phase-III trial (with 1,500 patients at 14 locations) after clearances,” said Balram Bhargava, DG, ICMR.

Apart from Novavax-SII trials, other drugmakers such as Pfizer Inc and Moderna Inc have already begun large late-stage studies of their experimental vaccines.

Health

Bihar deputy CM Sushil Kumar Modi tests positive for Covid-19, admitted to AIIMS Patna

“Tested positive for CORONA.All parameters perfectly normal.Started with mild temp.No temp.for last 2 days.Admitted to AIIMS Patna for better monitoring.CT scan of lungs normal. Will be back soon for campaigning,” Modi said in the tweet.

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Sushil Modi

Deputy chief minister of Bihar, Sushil Kumar Modi, tested positive for the coronavirus disease (Covid-19) on Thursday afternoon. The BJP leader announced this on Twitter and said he has been admitted to the All India Institute of Medical Sciences (AIIMS) in Patna. Modi said that his parameters are perfectly normal adding that he will be back soon for campaigning.

“Tested positive for CORONA.All parameters perfectly normal.Started with mild temp.No temp.for last 2 days.Admitted to AIIMS Patna for better monitoring.CT scan of lungs normal.Will be back soon for campaigning,” Modi said in the tweet.

Ahead of the assembly elections in Bihar, Modi held a joint campaign with chief minister and JD (U) leader Nitish Kumar at Buxar and Bhojpur districts on Sunday. The BJP and the JD(U) are jointly contesting the elections which will be held in three phases – October 28, November 3 and November 7. Votes will be counted on November 10.

Meanwhile, Bihar has registered over 208,000 Covid-19 cases till now which includes 196,208 recoveries, 11,010 active cases and 1,019 deaths. Over 9.5 million samples have been tested so far, the state health department bulletin showed.

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Cities

Another plea for release of nurse’s salaries reaches Delhi High Court

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Doctors Protest for Salary
Doctors Protest for Salary (File)

New Delhi, Oct 22 : The Delhi High Court will, on November 4, hear a plea seeking direction to release the salaries and allowances of the nursing staff at the Rajan Babu Institute of Pulmonary Medicine and Tuberculosis, under the North Delhi Municipal Corporation, pending since June this year.

The matter was listed before a division bench of Chief Justice D.N. Patel and Justice Prateek Jalan on Wednesday but got adjourned as the bench didn’t assemble.

The petition, filed by the Delhi Nurses Union, also sought directions to release the nursing personnel staff’s arrears since January 2016 pertaining to the Central Pay Commission bonus, Dearness Allowance, Leave Travel Concession, etc.

The plea further states that nursing personnel have been presently collectively working vigorously in the detection of coronavirus as well by conducting home visits, virtual community meetings, contact tracing, organising Covid-19 tests, comorbidity evaluation, ensuring regular medication, defaulter patients visits, record maintenance, etc.

“The nursing personnel, in accordance with the service conditions, are lawfully entitled to regularly receive the monthly salary along with all the associated allowances and benefits,” the plea said.

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Health

BJP leader Shahnawaz Hussain tests positive for coronavirus

Bharatiya Janata Party (BJP) leader Shahnawaz Hussain said he has tested positive for coronavirus on Wednesday.

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shahnawaz hussain

Bharatiya Janata Party (BJP) leader Shahnawaz Hussain said he has tested positive for coronavirus on Wednesday. He said he got himself tested after exhibiting symptoms and appealed to those who came in contact with him over the past few days to check if they too were infected.

“I had come in contact with few people who tested positive for Covid 19. I got myself tested today & my report has come positive. Request all who came in contact with me in last few days, kindly get yourself tested according to Govt guidelines” Hussain tweeted.

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