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Risk of hearing loss in menopausal women during hormone therapy

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London, May 15: Hormone replacement drugs may increase the risk of becoming deaf in older women , study says.

Oestrogens is female sex hormone, helps in hormone replacement therapy treatment reduces hot flashes and vaginal dryness and sometimes osteoporosis, condition where bones become weak.

According to studies, decrease in oestrogen levels may increase the risk for hearing loss at menopause.

“Many factors contribute to acquired hearing loss, including age, genetics, noise, medical conditions, diet and lifestyle factors. Our research focuses on identifying preventable contributors to hearing loss,” lead author Sharon Curhan at Brigham and Women’s Hospital in Massachusetts, was quoted as saying by express.co.uk.

“Although the role of sex hormones in hearing is complex and not completely understood, these findings suggest that women who undergo natural menopause at an older age may have a higher risk,” she added.

Study was done on 80,972 women for finding independent links between menopausal status, oral hormone therapy, and risk of self-reported hearing loss.

23 per cent of the result showed the positive response in hearing loss.

Although no significant association find between menopausal status and risk of hearing loss.

Wefornews Bureau

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AIIMS JPNATC MS replaced after report on journo’s death filed

The journalist worked for a Hindi daily and lived with his wife and two children in northeast Delhi”s Bhajanpura.

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Harsh Vardhan

New Delhi, July 11 : Union Minister for Health and Family Welfare Harsh Vardhan ordered immediate replacement of Medical Superintendent of AIIMS Jai Prakash Narayan Apex Trauma Centre (JPNATC) after a 4-member inquiry committee constituted to examine the suicide of journalist Tarun Sisodiya submitted its reported.

The report submitted by the committee on Friday said that no malafide intent was found in the death of the journalist.

“Directed that an expert committee be constituted to suggest suitable changes in administration, for AIIMS as well as JPNATC. The report, along with its recommendations, shall be submitted before me by July 27, 2020,” Harsh Vardhan tweeted.

“The committee did not find any malafide intent in the death of Mr Sisodiya. It also did not find any lapses in the treatment protocol of #Covid19,” he said.

Earlier, a 37-year-old journalist undergoing treatment for COVID-19 at the AIIMS Trauma Centre in Delhi since June 24 died after allegedly jumping off the fourth floor of the hospital building on July 6.

The journalist worked for a Hindi daily and lived with his wife and two children in northeast Delhi”s Bhajanpura.

Following the incident, Union Health Minister then asked the AIIMS Director to set a panel to probe the matter.

He was making significant recovery from COVID symptoms. He earlier underwent a surgery for frontal lobe meningioma (a type of brain tumour) at the G B Pant hospital in March 2020.

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India May See 2.87 Lakh Covid Cases A Day By Winter 2021: MIT Study

The world may witness 249 million (24.9 crore) cases and 1.8 million (18 lakh) deaths by spring 2021 if there are no effective treatments or vaccination.

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COVID-19 pandemic

In the absence of a COVID-19 vaccine or drugs, the researchers from Massachusetts Institute of Technology (MIT) have warned that India might record 2.87 lakh coronavirus cases per day by the end of winter 2021.

The world may witness 249 million (24.9 crore) cases and 1.8 million (18 lakh) deaths by spring 2021 if there are no effective treatments or vaccination, according to the study conducted by the researchers Hazhir Rahmandad, TY Lim and John Sterman of MIT’s Sloan School of Management.

“In this paper, we build and estimate a multi-country model of the Covid-19 pandemic at a global scale,” the study authors wrote.

Also Read: The Mysterious World Of Viruses And Why You Can’t Escape Them

For the findings, the MIT research team use a multi-country modified SEIR (Susceptible, Exposed, Infectious, Recovered) model, a standard mathematical model for infectious diseases used by epidemiologists, to simultaneously estimate the transmission of Covid-19 in 84 countries (4.75 billion people).

The model tracked community transmission, excluding the global travel network and instead separately estimating the date of introduction of patient zero for each country.

Within each country, the core of the model tracks the population through susceptible, pre-symptomatic, infected pre-testing, infected post-testing, and recovered states.

“Our model captures transmission dynamics for the disease, as well as how, at the country level, transmission rates vary in response to risk perception and weather, testing rates condition infection and death data, and fatality rates depend on demographics and hospitalisation,” they explained.

According to the study, the top 10 countries by projected daily infection rates at the end of winter 2021 are India, US, South Africa, Iran, Indonesia, Nigeria, Turkey, France and Germany.

Also Read: Our Live-in Virus: What Does the Real Covid Map Look Like?
India will be the worst affected country due to coronavirus followed by the US (95,000 cases per day), South Africa (21,000 cases per day) Iran (17,000 cases per day), and Indonesia (13,000 cases per day) at the end of winter 2021.

The MIT researchers also said that Infections are 12 times higher and deaths 50 per cent higher than previously reported.

“While actual cases are far greater than official reports suggest, the majority of people remain susceptible. Waiting for herd immunity is not a viable path out of the current pandemic,” Rahmandad said.

“Every community needs to keep the pandemic under control until a vaccine or treatment is widely available. A slow and half-hearted response only increases the human costs without offering much of an upside in terms of economic output,” Rahmandad noted.

Also Read: Did The Lockdown Work? What Did It Do? What Would Have Happened Without It?
As of Wednesday morning, the overall number of global COVID-19 cases has increased to more than 11.7 million, while the deaths have soared to over 543,000, according to Johns Hopkins University.

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Covid-19 can cause delirium, brain inflammation: Study

Research team identified one rare and sometimes fatal inflammatory condition, known as ADEM, which appears to be increasing in prevalence due to the pandemic

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Brain.

COVID-19 can cause severe neurological complications, including delirium, brain inflammation, stroke and nerve damage, warn researchers.

Published in the journal Brain, the research team identified one rare and sometimes fatal inflammatory condition, known as ADEM, which appears to be increasing in prevalence due to the pandemic.

Some patients in the study did not experience severe respiratory symptoms, and the neurological disorder was the first and main presentation of COVID-19, the researchers said.

“We identified a higher than expected number of people with neurological conditions such as brain inflammation, which did not always correlate with the severity of respiratory symptoms.” said study senior author Dr Michael Zandi from the University College London (UCL) in the UK.

The current study provides a detailed account of neurological symptoms of 43 people (aged 16-85) treated at the National Hospital for Neurology and Neurosurgery, UCLH, who had either confirmed or suspected COVID-19.

The researchers identified 10 cases of transient encephalopathies (temporary brain dysfunction) with delirium, which corresponds with other studies finding evidence of delirium with agitation.

There were also 12 cases of brain inflammation, eight cases of strokes, and eight others with nerve damage, mainly Guillain-Barre syndrome (which usually occurs after a respiratory or gastrointestinal infection).

Most (nine out of 12 cases) of those with brain inflammation conditions were diagnosed with acute disseminated encephalomyelitis (ADEM).

ADEM is rare and typically seen in children and can be triggered by viral infections: the team in London normally sees about one adult patient with ADEM per month, but that increased to at least one per week during the study period.

In some patients, the researchers found evidence that the brain inflammation was likely caused by an immune response to the disease, suggesting that some neurological complications of COVID-19 might come from the immune response rather than the virus itself.

The findings showed that the virus causing COVID-19, SARS-CoV-2, was not detected in the cerebrospinal brain fluid of any of the patients tested, suggesting the virus did not directly attack the brain to cause the neurological illness.

According to the team, further research is needed to identify why patients were developing these complications.

“Doctors needs to be aware of possible neurological effects, as early diagnosis can improve patient outcomes. People recovering from the virus should seek professional health advice if they experience neurological symptoms,” the study authors wrote.

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