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Mushrooms may have anti-ageing potential: Scientists

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New York, Nov 10: Mushrooms may contain unusually high amounts of two anti-oxidants that some scientists suggest could help fight ageing and age-related diseases.

Mushrooms have high amounts of the ergothioneine and glutathione, both important antioxidants, said Robert Beelman, Professor Emeritus at Pennsylvania State University in the US.

“What we found is that, without a doubt, mushrooms are highest dietary source of these two antioxidants taken together, and that some types are really packed with both of them,” said Beelman.

When the body uses food to produce energy, it also causes oxidative stress because some free radicals are produced, Beelman said.

The study published in the journal Food Chemistry suggests that the amounts of ergothioneine and glutathione in mushrooms vary by species with the porcini species, a wild variety, containing the highest amount of the two compounds among the 13 species tested.

“We found that the porcini has the highest, by far, of any we tested,” said Beelman. “This species is really popular in Italy where searching for it has become a national pastime.”

The more common mushroom types, like the white button, had less of the antioxidants, but had higher amounts than most other foods, Beelman said.

Free radicals are oxygen atoms with unpaired electrons that cause damage to cells, proteins and even DNA as these highly reactive atoms travel through the body seeking to pair up with other electrons.

“There’s a theory — the free radical theory of aging — that’s been around for a long time that says when we oxidize our food to produce energy there’s a number of free radicals that are produced that are side products of that action and many of these are quite toxic,” Beelman said.

Replenishing antioxidants in the body, then, may help protect against this oxidative stress.

The amount of ergothioneine and glutathione appear to be correlated in mushrooms, the researchers said.

Mushrooms that are high in glutathione are also high in ergothioneine, for example.

Cooking mushrooms does not seem to significantly affect the compounds, Beelman said.

The researchers said that future research may look at any role that ergothioneine and glutathione have in decreasing the likelihood of neurodegenerative diseases, such as Parkinson’s disease and Alzheimer’s disease.

“It’s preliminary, but you can see that countries that have more ergothioneine in their diets, countries like France and Italy, also have lower incidences of neurodegenerative diseases, while people in countries like the United States, which has low amounts of ergothioneine in the diet, have a higher probability of diseases like Parkinson’s Disease and Alzheimer’s,” Beelman said.

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High Vitamin D levels may reduce breast cancer risk

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New York, June 16: Higher levels of Vitamin D among women may reduce their risk of developing breast cancer post menopause, claimed a new study.

The study found that women with blood levels of serum 25-hydroxyvitamin D (OH) — the main form of vitamin D in blood — above 60 ng/ml (nanograms per millilitre) had one-fifth the risk of breast cancer compared to those with less than 20 ng/ml.

Thus, researchers from the University of California-San Diego determined that the minimum healthy level of 25(OH) in blood plasma should be 60 ng/ml, instead of the earlier recommended higher than the 20 ng/ml.

“Increasing Vitamin D blood levels substantially above 20 ng/ml appears to be important for the prevention of breast cancer,” said lead author Sharon McDonnell from GrassrootsHealth, a non-profit public health research organisation.

The study, published in the journal PLOS ONE, analysed data from two randomised clinical trials with 3,325 combined women and a prospective study involving 1,713 women with average age of 63.

Participants were free of cancer at enrollment and were followed for a mean period of four years. Vitamin D levels in blood were measured during study visits.

“This study was limited to postmenopausal breast cancer. Further research is needed on whether high 25(OH)D levels might prevent premenopausal breast cancer,” said Cedric F. Garland from UC-San Diego.

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Congenital Heart Disease Often Lead To Mental Illness

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WORLD HEART DAY

More than 1.5 lac infants are born in India annually with congenital heart disease. Around 78,000 infants die of congenital heart disease in India every year.

So What Is Congenital Heart Disease?

Congenital Heart Disease (CHD) is when a child is born with an abnormality in his/her heart. It could be abnormal in the way it’s structured (have parts of the organ missing, have functional problems and/or holes in the chambers. Doctors are often able to diagnose CHD while the child is still in the womb of the mother. CHD is considered to be a life threatening illness and hence can cause emotional turmoil in parents of the child, which in turn affects the psychological development of the unborn child.

Additional alterations immediately after birth for a child can prove to be traumatic, and cause PTSD like symptoms later on in life. For example, a child is often separated from the child’s mother and placed in intensive care immediately after birth, and then they are subjected to invasive medical procedures and tests. An infant with CHD goes through a traumatic event which is often reflected in feeding problems, nightmares and over all behavior of the infant.

According to Dr.Vihan Sanyal, psychotherapist, “Parents of children with CHD can seek the help of a skilled psychotherapist for their children’s psychological health while they are children. This will give the therapist to address the issue early on and help improve the quality of life of the child well into adulthood”

Early stressful experiences of a child can alter the child’s brain development, affect their immune system (the child tends to fall sick more often) and disturb the way a child reacts to stressful events in future life. Studies have proven that children who have been exposed to highly stressful environments early on in childhood often have issues with cognition and in processing of emotions.

Neonatal care, pediatric care, adolescent years and adulthood of a person diagnosed with CHD is often complex and challenging for the person. The psychological impact this creates is profound and can lead to suicide in adulthood if not managed properly.

Dr.Sanyal explains: “Children with CHD have difficulties with motor skills, speech, focus & attention, executive functioning, impulse control, management of emotions and behavior. The change in the structure of the brain and in brain chemistry can tarnish the image a child has of himself. He can quickly form an opinion of himself as being “abnormal”, leading to self esteem issues. It is important for children to be helped by a skilled psychotherapist, who is proficient in dealing with psychological issues of children living with CHD. Timely therapeutic intervention can provide the support a child requires in coping with the emotional challenges of CHD.”

Psychiatric disorders, in particular mood and anxiety disorders are more frequent in Adults with CHD compared to Non-CHD adults.

Life threat to the fetus is an important key factor for emotional disturbance during pregnancy for the parents. It is also an indication of long term psychological disorders faced by the parents of the child with CHD.

Studies have indicated that more than 30% of parents with children who have been diagnosed with CHD show signs of Post Traumatic Stress Disorder (PTSD). 50% of them have shown to have anxiety and depression. More than 80% of these parents have tested positive for psychological stress related disorders.

“MNLP & other modalities of psychotherapy can help the parents of those who have recently been diagnosed with CHD. MNLP can help in building resilience in the parents and equip them to face the challenges which lay ahead without disintegrating emotionally. Hypnotherapy can be used to promote relaxation and to address issues of trauma in the subconscious” Say’s Dr.Sanyal

Contributory Factors While Pregnant Which Can Result In CHD

· Smoking during pregnancy

· Consuming alcohol during pregnancy

· Exposure To Poor Air Quality (pollution)

· Exposure to Toxic Chemicals (Even common household chemicals like toilet cleaners and detergents)

· Exposure to pesticides and insecticides

· Medicines not meant to be consumed during pregnancy

· Obesity in mothers

In addition to the above list, symptoms of anxiety and depression in pregnant women often go undetected and hence, remain untreated. It is also important to mention that a range of symptoms of stress, anxiety and depression, marital harmony and quality of relationship the parents share with each other all have an effect on the fetus’s psychological health.

Dr.Sanyal says: “Many pregnant women of our country are unaware of some of the precautions they need to take during pregnancy. More importantly, they are unaware of the harmful effects the unborn child could face due to their habit and behavior. Many psychological disorders and mental illnesses can be prevented by pregnant women choosing to lead a balanced and a relatively stress free life during their pregnancy.”

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Can sleeping more affect your heart?

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Seoul, June 13: If you thought that only less hours of sleep would affect your health, then you are wrong. Sleeping more than 10 hours per day is also associated with metabolic syndrome, raising the risk for heart diseases, according to a new study.

Those who slept for over 10 hours daily were at risk of elevated waist circumference, high triglyceride levels — a type of fat, low levels of “good” cholesterol, hypertension as well as high fasting blood sugar — referred to as metabolic syndrome and associated with increased risk of cardiovascular diseases.

While sleeping more raised triglycerides levels in both men and women, in women it led to higher waist circumference, blood sugar as well as lower levels of “good” cholesterol.

Conversely, getting less than six hours of sleep was associated with higher risk of metabolic syndrome in men and higher waist circumference among both men and women, researchers said.

“This is the largest study examining a dose-response association between sleep duration and metabolic syndrome and its components separately for men and women,” said lead author Claire E. Kim from Seoul National University College of Medicine in South Korea.

The study, published in the journal BMC Public Health, included data from 1,33,608 participants aged between 40-69 years. The results showed that the prevalence of metabolic syndrome was just over 29 per cent in men and 24.5 per cent in women.

“We observed a potential gender difference between sleep duration and metabolic syndrome, with an association between metabolic syndrome and long sleep in women and metabolic syndrome and short sleep in men,” said Kim.

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