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Moderna COVID-19 vaccine appears safe, shows signs of working in older adults – study

Moderna is already testing the higher dose in a large Phase III trial, the final stage before seeking emergency authorization or approval.

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COVID-19 Vaccine

Results from an early safety study of Moderna Inc’s MRNA.O coronavirus vaccine candidate in older adults showed that it produced virus-neutralizing antibodies at levels similar to those seen in younger adults, with side effects roughly on par with high-dose flu shots, researchers said on Tuesday.

The study, published in the New England Journal of Medicine, offers a more complete picture of the vaccine’s safety in older adults, a group at increased risk of severe complications from COVID-19.

The findings are reassuring because immunity tends to weaken with age, Dr. Evan Anderson, one of the study’s lead researchers from Emory University in Atlanta, said in a phone interview.

The study was an extension of Moderna’s Phase I safety trial, first conducted in individuals aged 18-55. It tested two doses of Moderna’s vaccine – 25 micrograms and 100 micrograms – in 40 adults aged 56 to 70 and 71 and older.

Overall, the team found that in older adults who received two injections of the 100 microgram dose 28 days apart, the vaccine produced immune responses roughly in line with those seen in younger adults.

Moderna is already testing the higher dose in a large Phase III trial, the final stage before seeking emergency authorization or approval.

Side effects, which included headache, fatigue, body aches, chills and injection site pain, were deemed mainly mild to moderate.

In at least two cases, however, volunteers had severe reactions.

One developed a grade three fever, which is classified as 102.2 degrees Fahrenheit (39°C) or above, after receiving the lower vaccine dose. Another developed fatigue so severe it temporarily prevented daily activities, Anderson said.

Health

Bihar deputy CM Sushil Kumar Modi tests positive for Covid-19, admitted to AIIMS Patna

“Tested positive for CORONA.All parameters perfectly normal.Started with mild temp.No temp.for last 2 days.Admitted to AIIMS Patna for better monitoring.CT scan of lungs normal. Will be back soon for campaigning,” Modi said in the tweet.

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Sushil Modi

Deputy chief minister of Bihar, Sushil Kumar Modi, tested positive for the coronavirus disease (Covid-19) on Thursday afternoon. The BJP leader announced this on Twitter and said he has been admitted to the All India Institute of Medical Sciences (AIIMS) in Patna. Modi said that his parameters are perfectly normal adding that he will be back soon for campaigning.

“Tested positive for CORONA.All parameters perfectly normal.Started with mild temp.No temp.for last 2 days.Admitted to AIIMS Patna for better monitoring.CT scan of lungs normal.Will be back soon for campaigning,” Modi said in the tweet.

Ahead of the assembly elections in Bihar, Modi held a joint campaign with chief minister and JD (U) leader Nitish Kumar at Buxar and Bhojpur districts on Sunday. The BJP and the JD(U) are jointly contesting the elections which will be held in three phases – October 28, November 3 and November 7. Votes will be counted on November 10.

Meanwhile, Bihar has registered over 208,000 Covid-19 cases till now which includes 196,208 recoveries, 11,010 active cases and 1,019 deaths. Over 9.5 million samples have been tested so far, the state health department bulletin showed.

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Cities

Another plea for release of nurse’s salaries reaches Delhi High Court

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Doctors Protest for Salary
Doctors Protest for Salary (File)

New Delhi, Oct 22 : The Delhi High Court will, on November 4, hear a plea seeking direction to release the salaries and allowances of the nursing staff at the Rajan Babu Institute of Pulmonary Medicine and Tuberculosis, under the North Delhi Municipal Corporation, pending since June this year.

The matter was listed before a division bench of Chief Justice D.N. Patel and Justice Prateek Jalan on Wednesday but got adjourned as the bench didn’t assemble.

The petition, filed by the Delhi Nurses Union, also sought directions to release the nursing personnel staff’s arrears since January 2016 pertaining to the Central Pay Commission bonus, Dearness Allowance, Leave Travel Concession, etc.

The plea further states that nursing personnel have been presently collectively working vigorously in the detection of coronavirus as well by conducting home visits, virtual community meetings, contact tracing, organising Covid-19 tests, comorbidity evaluation, ensuring regular medication, defaulter patients visits, record maintenance, etc.

“The nursing personnel, in accordance with the service conditions, are lawfully entitled to regularly receive the monthly salary along with all the associated allowances and benefits,” the plea said.

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Health

BJP leader Shahnawaz Hussain tests positive for coronavirus

Bharatiya Janata Party (BJP) leader Shahnawaz Hussain said he has tested positive for coronavirus on Wednesday.

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shahnawaz hussain

Bharatiya Janata Party (BJP) leader Shahnawaz Hussain said he has tested positive for coronavirus on Wednesday. He said he got himself tested after exhibiting symptoms and appealed to those who came in contact with him over the past few days to check if they too were infected.

“I had come in contact with few people who tested positive for Covid 19. I got myself tested today & my report has come positive. Request all who came in contact with me in last few days, kindly get yourself tested according to Govt guidelines” Hussain tweeted.

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Corona Virus (COVID-19) Live Data

COVID-19 affects different people in different ways. Most infected people will develop mild to moderate illness and recover without hospitalization.