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Late childbirth linked to high breast cancer risk

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New York, Dec 11: Women who had their first child after 35 may be at an increased risk of developing breast cancer than their peers who do not have children, according to a study contrary to conventional wisdom that childbirth is protective against breast cancer.

Besides late childbirth, women who had a family history of breast cancer or who had a greater number of births also had an increased risk for breast cancer after childbirth. The pattern looked the same whether or not women breastfed.

While the risk was higher for women who were older at first birth, there was no increased risk of breast cancer after a recent birth for women who had their first child before 25, said researchers from the University of North Carolina (UNC) in the US.

“This is evidence of the fact that just as breast cancer risk factors for young women can differ from risk factors in older women, there are different types of breast cancer, and the risk factors for developing one type versus another can differ,” said Hazel B. Nichols, Professor at the UNC.

Although childbirth is still protective against breast cancer, researchers say it can take more than two decades for benefits to emerge.

Breast cancer is more common in older women, with the median age of 62 at diagnosis. But, the study, published in the Annals of Internal Medicine, identified elevated breast cancer risk after childbirth in women younger than 55.

In women 55 years and younger, breast cancer risk peaked about five years after they gave birth, with risk for mothers 80 per cent higher compared with women who did not gave birth.

Twenty-three years after giving birth, women saw their risk level off, and pregnancy started to become protective.

For their analysis, the team pooled data from 15 prospective studies from around the globe that included 889,944 women. In addition to looking at breast cancer risk after childbirth, they also evaluated the impact of other factors such as breastfeeding and a family history of breast cancer.

The findings could be used to develop better breast cancer risk prediction models to help inform screening decisions and prevention strategies, Nichols said.

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Natural ways to boost immunity in children

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New Delhi, Jan 21: It is natural for parents to protect their children from any harm, including the endless array of germs they are exposed to every day.

As children grow up, they are continuously exposed to various germs, especially in places such as daycare centres and preschool. Children with low immunity are highly susceptible to various types of infections. The high incidence of infections has led to an increased and inappropriate use of antibiotics, which has further resulted in antimicrobial resistance.

Antimicrobial resistance, a widespread problem, takes places when microbes build resistance against the medications intended to kill them due to overuse. It is one of the world’s most pressing public health problems. The best way to tackle this is to build a strong immunity, which naturally protects your child from infections. Dr. Rajesh Kumawat, Head – Medical Services & Clinical Development, The Himalaya Drug Company, shares a few tips that can help boost your child’s immunity.

Healthy Diet

A healthy diet that comprises all fundamental components like proteins, minerals, vitamins, micronutrients and unsaturated fats in optimum quantity, helps build the immunity required to fight against various infections or diseases in children. Citrus fruits, carrots, green leafy vegetables, beans, strawberry, yogurt, garlic, and ginger help build immunity with their immunity-boosting properties.

Adequate Sleep

Sleep deprivation suppresses the functionality of the immune system, which makes children susceptible to infections. Adequate sleep is an absolute necessity to rejuvenate the body. Newborns need up to 18 hours of sleep a day, toddlers require 12 to 13 hours, and preschoolers need about 10 hours of sleep.

Hygiene

Maintaining hand hygiene before and after each meal, after playtime, handling pets, blowing the nose, using the restroom and arriving home from daycare helps prevent infections in children.

Herbal Solutions

Despite taking proper care, children’s immunity may be affected. Consumption of herbal dietary supplements like Guduchi (Tinospora cordifolia), Amalaki (Emblica officinalis), Yashtimadhu (Glycyrrhiza glabra), and Guggulu (Balsamodendron mukul) can help children stay healthier as they help build immunity.

“Naturally obtained supplements strengthen the immune system. Herbs like Guduchi, Yashti Madhu, and Guggulu are natural sources of antioxidants. The antiviral property of Yashtimadhu also helps manage asthma, bronchitis, and chronic cough. The anti-inflammatory property of Guggulu helps reduce inflammation,” Dr. Kumawat added.

“Naturally obtained supplements strengthen the immune system. Herbs like Guduchi, Yashti Madhu, and Guggulu are natural sources of antioxidants. The antiviral property of Yashtimadhu also helps manage asthma, bronchitis, and chronic cough. The anti-inflammatory property of Guggulu helps reduce inflammation,” Dr. Kumawat added.

A combination of herbs may be a safe and effective adjuvant to antimicrobials in the management of recurrent infections. When co-prescribed with antibiotics, herbs may
have a role in faster recovery, reduces the duration and cost of therapy, besides preventing reinfections.

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Anti-inflammatory drugs may put you at heart attack risk

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If you have been hit by the winter cold and are thinking about taking medicines that relieve your aches, pains and congestion, be careful. Those may also put your heart at risk, the American Heart Association has warned.

A study has showed that both decongestants and non-steroidal anti-inflammatories (NSAIDs), found in many cold medicines, were listed as medications that could increase blood pressure.

People who used NSAIDs while sick were more than three times as likely to have a heart attack within a week compared with the same time period about a year earlier when participants were neither sick nor taking an NSAID.

“People with uncontrolled high blood pressure or heart disease should avoid taking oral decongestants. And for the general population or someone with low cardiovascular risk, they should use them with the guidance of a health care provider,” said Sondra DePalma, from the University of Pittsburgh in the US.

Decongestants like pseudoephedrine or phenylephrine constrict blood vessels. They allow less fluid into your sinuses, “which dries you up”, said Erin Michos, associate director of preventive cardiology at the Johns Hopkins Univerity’s Ciccarone Center in Baltimore.

The biggest concerns are for people who have had a heart attack or stroke, or have heart failure or uncontrolled high blood pressure, Michos said, in the paper published in the Journal of Infectious Diseases.

Importantly, healthy people might also be at risk.

For the study, researchers looked at nearly 10,000 people with respiratory infections who were hospitalised for heart attacks.

Participants were 72 years old on average at the time of their heart attacks and many had cardiovascular risk factors, such as diabetes and high blood pressure.

People who are sick should use both classes of medications — decongestants and NSAIDs — judiciously and understand the potential side effects.

In addition, decongestants should not be taken longer than seven days before consulting with a healthcare provider, DePalma said.

One should also rest and drink plenty of fluids if symptoms are mild or moderate, DePalma noted.

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What is to be blamed for childhood cancer?

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A team of researchers has thrown light on the community beliefs about what causes cancer in children, an area which remains understudied, finds a latest research.

“Few childhood cancers are attributed to genetics or environmental factors, so when children are diagnosed with cancer, families often wonder ‘why me/why us’?” said lead author Janine Vetsch, postdoctoral research candidate from UNSW Sydney in Australia.

For the study, the team examined the beliefs of more than 600 participants — parents and childhood cancer survivors — about the causes of childhood cancer, and compared them with beliefs of 510 members of the general population.

Findings, published in Acta Oncologica, revealed that more than seven out of 10 childhood cancer survivors and survivors’ parents believed that chance or bad luck caused the cancer.

This led to most parents and survivors seem to understand that there is nothing they could have done to prevent the cancer, according to Vetsch.

However, around one in five families did believe that environmental factors and genetics played a role, despite only limited available scientific evidence, results further showed.

“It looks like healthcare professionals are successfully helping most families arrive at that view,” said Vetsch.

Such views could lead to stigma. Hence, it is important to increase community knowledge of childhood cancer causes in general.

There is a need to encourage doctors to talk about the causes with affected families to address unhelpful misconceptions,” Vetsch suggested.

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