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Just 1 dose of the HPV vaccine may prevent infection: Study

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New York, Just one dose of the human papillomavirus (HPV) vaccine may prevent infection from potential cancer-causing virus, suggests new research.

Results of the study, which included only women participants published in the journal JAMA Network Open, suggest that a single dose of HPV vaccine may be as effective as the currently recommended two- or three-dose series.

However, it is too early for people to rely on a single dose of the vaccine for protection, according to senior author Ashish Deshmukh, Assistant Professor at The University of Texas Health Science Center at Houston (UTHealth).

“HPV vaccine coverage is less than 10 per cent globally because of poor vaccine uptake rates in many resource-limited countries. Ensuring boys and girls receive their first dose is a big challenge in several countries and a majority of adolescents are not able to complete the recommended series due to a lack of intensive infrastructure needed to administer two or three doses,” Deshmukh said.

“If ongoing clinical trials provide evidence regarding sustained benefits of a one-dose regimen, then implications of single-dose strategy could be substantial for reducing the burden of these cancers globally,” he added.

According to the US Centers for Disease Control (CDC), 34,800 new cancer diagnoses are linked to HPV annually. The virus is thought to account for more than 90 per cent of all cervical and anal cancers, more than 60 per cent of all penile cancers, and approximately 70 per cent of all oral cancers.

Although the study participants included only women, the CDC recommends a two-dose regimen for all children, starting the series before age 15, or a three-dose regimen if the series is started between ages 16 to 26.

The latest generation of HPV vaccine can protect against nearly 90 per cent of cancer-causing HPV infections.

Yet, current vaccinations rates are less than ideal. The current HPV vaccine dosing regimen can be cumbersome for people to understand. If one dose is proven effective in trials, the vaccine regimen will be simplified,” said UTHealth School of Public Health assistant professor and lead author Kalyani Sonawane.

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Novel predicted coronavirus 40 years ago, Internet stumped

As the post went viral, Twitterati flooded the social media with their reactions.

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New Delhi, Feb 17: An excerpt of the Novel “The Eyes of Darkness”, a 1981 thriller by bestselling suspense author Dean Koontz is revolving around the social media which tells of a Chinese military lab that creates a virus as part of its biological weapons programme.

In chapter 39 of his book, Koontz writes that the lab is located in Wuhan, which lends the virus its name, Wuhan-400.

Congress leader Manish Tewari has also tweeted excerpts from a book that went viral on the Internet that the coronavirus involved in the outbreak in China’s Wuhan appears to be man-made.

“Is Coranavirus a biological Weapon developed by the Chinese called Wuhan -400? This book was published in 1981. Do read the excerpt,” Congress leader Manish Tewari tweeted.

Tewari highlighted a paragraph that read: “They call the stuff ‘Wuhan-400’ because it was developed at their RDNA labs outside of the city of Wuhan, and it was the four hundredth viable strain of man-made micro-organisms created at that centre.”

As the post went viral, Twitterati flooded the social media with their reactions.

A user wrote, “Haha Infinite monkey theorem. Pick any event and chances are that some book written at some would have a similar plot . Conspiracy theory has no end.”

Another wrote, “Sensational … No doubt China had replaced Russia and USSR as rogue country in Hollywood films and later James Bond movies.”

A post read, “Intriguing for sure, hope the truth comes out.”

A user remarked, “Okay if it is then it surely backfired on them!”

By the end of Sunday, a total of 1,770 people had died of the disease and 70,548 confirmed cases of novel coronavirus infection had been reported in 31 provincial-level regions and the Xinjiang Production and Construction Corps in China.

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WHO underestimates coronavirus’ ability to spread: Study

The World Health Organization estimates that the coronavirus has a transmissibility, expressed as a reproduction number, of between 1.4 and 2.5.

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London, Feb 15 : The novel coronavirus may have greater ability to spread than the World Health Organization (WHO) has estimated so far, according to a review of previous studies of the virus’ transmissibility.

“Our review shows that the coronavirus is at least as transmissible as the SARS virus. And that says a great deal about the seriousness of the situation,” said Joacim Rocklov, Professor of Sustainable Health at Umea University in Sweden and one of the authors of the study, published in the Journal of Travel Medicine.

The World Health Organization estimates that the coronavirus has a transmissibility, expressed as a reproduction number, of between 1.4 and 2.5.

A reproduction number is a measurement of how many people a contaminated person transmits the virus to in a previously healthy population.

The higher the number, the more transferable the virus is and the higher the risk of its rapid spread.

When the reproduction number falls below 1.0, the epidemic is likely to die out.

Researchers in Umea in Sweden, Heidelberg in Germany and Zhangzhou in China have carried out a review of several scientific studies of the novel coronavirus.

In total, the researchers found twelve studies of sufficiently high quality.

The studies consisted of estimations of the growth rate based upon the cases observed in the Chinese population, and based upon statistical and mathematical methods.

The earliest studies of the coronavirus indicated a relatively low transmissibility. Thereafter, the transmissibility rose rapidly to stabilise between 2-3 in the most recent studies.

The reproduction number in the studies summed up to a mean of 3.28, and a median of 2.79, which is significantly higher than the World Health Organization’s estimation of 1.4-2.5.

“When looking at the development of the corona epidemic, reality seems to correspond well to or even exceed the highest epidemic growth in our calculations. Despite all intervention and control activities, the coronavirus has already spread to a significantly higher extent than SARS did,” said Rocklov.

The overall death toll in China due to the deadly coronavirus on Saturday increased to 1,523, with a total of 66,492 confirmed cases, authorities said.

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Novel coronavirus to be called COVID-19: WHO

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COVID 19

New Delhi, Feb 12 : The deadly novel coronavirus has now got its official name. From now on, the virus will be known as ‘COVID-19’.

In a statement released by the World Health Organisation, its Director-General Dr Tedros Adhanom Ghebreyesus said, “we now have a name for the disease: COVID-19. I’ll spell it: C-O-V-I-D hyphen one nine – COVID-19.” He termed the virus as “a common enemy.”

The statement was released on Tuesday by the World Health Organisation.

The WHO chief also said that, “under agreed guidelines between WHO, the World Organisation for Animal Health and the Food and Agriculture Organization of the United Nations, we had to find a name that did not refer to a geographical location, an animal, an individual or group of people, and which is also pronounceable and related to the disease. Having a name matters to prevent the use of other names that can be inaccurate or stigmatizing. It also gives us a standard format to use for any future coronavirus outbreaks.”

According to the World Health Organisation there were 42,708 confirmed cases reported in China, and tragically the death toll surpassed 1000 deaths as on Tuesday. “1017 people in China have lost their lives due to this virus. Most of the cases and most of the deaths are in Hubei province. Outside China, there are 393 cases in 24 countries, and 1 death,” said Dr Ghebreyesus.

The world health body also said that it had activated a UN Crisis Management Team, to be led by Dr Mike Ryan that will help the organisation focus on the health response while the other agencies could bring their expertise to bear on the wider social, economic and developmental implications of the outbreak so we are all working to our strengths. Dr Mike Ryan will coordinate the whole UN response.

WHO is also hosting a two-day meeting of more than 400 scientists from around the world, both in person and virtually called Global research and innovation forum on February 11 and 12.

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