WeForNews | Latest News, Breaking News, News Updates It takes 18 months to develop good vaccine: Ex-ICMR chief | WeForNews | Latest News, Blogs
Connect with us

Disaster

It takes 18 months to develop good vaccine: Ex-ICMR chief

Published

on

Vaccine

New Delhi, July 4 : A good vaccine usually takes at least 18 months, before it could be rolled out for production after fast-tracking all the mandatory regulatory approvals, said N.K. Ganguly, former director general of Indian Council of Medical Research (ICMR).

It is expected that India”s first indigenous Covid-19 vaccine, Covaxin may be released on August 15 under a fast-track mechanism. According to the government”s top medical research body, a dozen institutes have been selected for clinical trials of the indigenous COVID-19 vaccine (BBV152 COVID vaccine). Ganguly said the strain of the virus was given to BBIL in May end, and in July, human trials have been scheduled.

Elaborating on the lengthy process involved in vaccine development, he insisted that after spending many months and infusing a lot of funds, the uncertainty continues to linger. “It may be difficult to say whether the vaccine is successful or not”, he added.

The ICMR in a letter said, “It is envisaged to launch the vaccine for public health use latest by August 15, after completion of all clinical trials. BBIL (Bharat Biotech International Limited) is working expeditiously to meet the target, however the final outcome will depend on the cooperation of all clinical trial sites involved in this project.”

Before the vaccine is tested on humans, challenge studies are done on mice and monkey, then a toxicology report is prepared, to check if the developed vaccine produces harm to cells, and it takes at least three to four months to finalize this report, said Ganguly. After this phase, the vaccine is tested on two rodents and a large animal and after successful completion of this stage the vaccine is ready for human trials.

“In Phase 1, the age group profiling is done (wherein vaccine study is done on people in different age groups). In Phase 2, nearly 600 to 700 people are vaccinated, and if the vaccine performs successfully in this phase then it progresses into Phase 3, which is called the efficacy study (in this phase, thousands of people are enrolled). Even after fast tracking regulatory approvals, it will take at least 18 months to develop a good vaccine”, said Ganguly.

He insisted that the vaccine being developed by Moderna (RNA vaccine is set to begin Phase 3 trials later this month and targets a vaccine by 2021) and BioNTech-Pfizer (Phase 3 trial is expected to begin in July). Gennova biopharmaceutical is also working on a vaccine and it looks positive, Ganguly added.

(Sumit Saxena can be contacted at [email protected])

Cities

Earthquake of magnitude 4.1 strikes Jammu and Kashmir

They said while the tremors caused panic among people, there were no reports of any loss of life or injury or damage to property.

Published

on

Earthquake Strong

Srinagar, Jan 16 : An earthquake of magnitude 4.1 hit Jammu and Kashmir on Saturday, but there was no report of any damage, officials said.

At 10:01 pm, the earthquake struck at a latitude of 33.03 degrees north and a longitude of 75.93 degrees east — 93 kms east of Katra, they added.

The depth of the earthquake was 10 kms, the officials said.

They said while the tremors caused panic among people, there were no reports of any loss of life or injury or damage to property.

Continue Reading

Blog

Covaxin consent form says vax administered without ph-3 trial

The vaccine is first offered to the healthcare workers, frontline workers and those above 50 years of age, followed by the below-50 population with comorbidities, and finally to the remaining population based on disease epidemiology and vaccine availability.

Published

on

By

COVAXIN Corona Covid vaccine

New Delhi, Jan 16 : Amid the vaccinaton drive against Covid-19, it has emerged that there is a separate consent form for those who are administered the ‘Covaxin‘ vaccine manufactured by Bharat Biotech.

The form says that “In phase-1 and phase-2 clinical trial ‘Covaxin’ has demonstrated the ability to produce antibodies against Covid-19, however the clinical efficacy of Covaxin is yet to be established and it is still being studied in phase-3 clinical trial, hence it is important to appreciate that receiving the vaccine does not mean that the other precautions related to Covid-19 should not be followed.”

The form says that in case of any adverse and serious condition, the receiver will be provided utmost care at the health centre and in case of casuality the compensation will be provided by Bharat Biotech.

“The compensation for serious adverse event will be paid by sponsor BBIL if the SAE is proven to be casually related to the vaccine,” it said.

Serious concerns were raised in certain quarters including by opposition parties and Congress leader Manish Tewari has questioned the efficacy of ‘Covaxin’ while the Prime Minister has warned people not to believe in “rumours”.

The world’s biggest vaccination drive come almost a year after the first coronavirus case was detected in India, and since then the deadly virus has claimed over 1.5 lakh lives and infected one crore people. The first case came to the fore on January 30, 2020 in Kerala.

Two vaccines — the Oxford vaccine ‘Covishield’ manufactured by the Serum Institute of India, and indigenously developed ‘Covaxin’ by Bharat Biotech — will be administered to priority groups. So far, the central government has procured 1.1 crore Covishield and 55 lakh Covaxin vaccines at a cost of Rs 200 and Rs 206 per dose, respectively.

In Delhi, which has 81 vaccination sites, ‘Covaxin’ has been allotted to six Centre-run hospitals while 75 Delhi government and private hospitals will receive ‘Covishield’.

The vaccine is first offered to the healthcare workers, frontline workers and those above 50 years of age, followed by the below-50 population with comorbidities, and finally to the remaining population based on disease epidemiology and vaccine availability.

Continue Reading

Disaster

Magnitude 6.7 Earthquake Hits Russia-Mongolia Border Region

The quake was at a depth of 10 kilometers

Published

on

Earthquake Strong

AN earthquake of magnitude 6.7 struck the Russia-Mongolia Border Region on Tuesday, the GFZ German Research Center for Geosciences said.

The quake was at a depth of 10 kilometers, it added.

The epicenter of the earthquake was registered 277 kilometers southwest of the city of Angarsk, in the Russian Irkutsk region, and 30 kilometers from the Mongolian city of Turt, Russian state-owned news agency Sputnik reported. https://bit.ly/2XtgrJs

There were no immediate reports of damage or victims, the report said.

Continue Reading
Advertisement

Most Popular