WeForNews | Latest News, Breaking News, News Updates As US President Donald Trump has again offered a diplomatic solution to North Korea by the so-called "freeze-for-freeze' option, meaning if Kim Jong un gives up its nuclear and missile development programs, the United States and its allies would in return freeze military exercises, while Israel and Saudi Arabia are forming an alliance to counter Iran in the Middle East which has the potential for the outbreak of World War III. | WeForNews | Latest News, Blogs
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World War III : Israel- Saudi alliance to counter Iran in Middle East while Trump plans to negotiate with Kim

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As US President Donald Trump has again offered a diplomatic solution to North Korea by the so-called “freeze-for-freeze’ option, meaning if Kim Jong un gives up its nuclear and missile development programs, the United States and its allies would in return freeze military exercises, while  Israel and Saudi Arabia are forming an alliance to counter Iran in the Middle East which has the potential for the outbreak of World War III.

In an unprecedented move, Israel’s top military chief expressed his willingness to form alliance with Saudi Arabia to counter Iran’s increasing dominance in the Middle East, thus preparing ground for the World War III scenario.

Lieutenant General Gadi Eisenkot deliberately gave an interview to Saudi-owned media,  though Saudi Arabia and Israel  do not enjoy any formal diplomatic relations, but are ready to work together in a “new international alliance” against Iran.

“We are ready to exchange experiences with moderate Arab countries and exchange intelligence to confront Iran,We are ready to share information if necessary. There are many common interests between us and them” the Israeli chief of staff said.

This strategic move comes after Kingdom displayed its power play by compelling Lebanese Prime Minister Saad Hariri to resign aimed at wrecking a delicate compromise with Hezbollah and taking a swipe at regional rival Iran.

Recent developments in Riyadh  also point to political instability where more than 200 people including princes, Businessmen and diplomats have been detained on the issues of corruption while critics see the detentions as an effort by the Saudi crown prince, Mohammed bin Salman, to neutralize  remaining power centers in the kingdom that could challenge his rule.

The  power struggle between Sunni led Saudi Arabia and Iran led Shia crescents started after the collapse of Kingdom’s economy in 2015  and escalated after Saudi backed forces started supporting anti-Shiite groups in Yemen, Syria  and elsewhere across the region.

But Russian President Vladimir Putin  and Iranian President Hassan Rouhani succedded in strenthening control of President  Bashar al -Assad in Syria and reversing the course of the civil war through their joint military campaign.

Russia, Turkey and Iran will hold summit talks on Syria next week as Ankara threatens a possible attack on U.S.-allied Kurdish forces and tensions rise between Moscow and Washington over the future of the war-torn state.

As the new international alliances are being stitched on the global stage, Russian President Vladimir Putin  will be hosting  his Turkish and Iranian counterparts, Recep Tayyip Erdogan and Hassan Rouhani, on Nov. 22 in the Black Sea resort of Sochi to discuss Syria and regional developments.

This move is a part of tussle between Moscow and Washington as Ankara, Tehran and Moscow spearheaded a cease-fire initiative and demanded the American forces to leave Damascus for ensuring a political settlement in Syria. Russian Foreign Ministry spokeswoman Maria Zakharova has branded the U.S.-led coalition as “practically occupying forces” because they’re operating in Syria without the agreement of the government in Damascus.

US President Donald Trump should make efforts to prevent the outbreak of World War III as there are  numerous chances such as

The world economy being in doldrums  (Europe’s, UK, Spain etc)

The Middle East has been rattled after the Spring revolution that started in mid-2012 and the 2011 toppling of Libyan strongman Muammar Gaddafi.

Gaddafi was successful in controlling the different ethnic and tribal groups in Libya and after his death the Libya is witnessing a civil war between rival groups seeking control of the territory of Libya. The conflict has been mostly between the government of the House of Representatives (HoR) that was elected democratically in 2014, also known as the “Tobruk government” and internationally recognized as the “Libyan government” and the rival General National Congress (GNC) endorsed government, also called the “National Salvation Government”, based in the capital Tripoli.

Chinese President Xi Jinping’s political ideology having been Enshrined in China’s Constitution has further complicated the entire world scenario as  Xi aggressively pursue his policy of seizing control of entire South China Sea ,border areas and parts of Indian Ocean.

There also exists Islamic terrorism ISIS who seek to establish their own hold in the world with no borders.

There is an increasing  number of countries where leaders are amending constitutions to become dictators.

There also a new trend of many parts in different countries that are struggling for autonomy from the respective countries  like Catalonia, Kashmir, Balochistan, Lombardy and Veneto, Scotland etc)

There are many insurgent groups existing in many  countries.

Saudi Arabia  had already suspended its diplomatic relations with Qatar by accusing it of “harbouring a multitude of terrorist and sectarian groups that aim to create instability in the region” and for having friendly ties with Iran. But Saudi’s bid to isolate Qatar has failed to achieve its goals. Both Israel and Riyadh convinced US President Donald Trump to de-certify the Iran nuclear deal.

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By: Arti Bali

Senior Journalist

DISCLAIMER : Views expressed above are the author’s own.

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Male sex hormones may help treat breast cancer: Study

While endocrine therapy is standard-of-care for estrogen receptor positive breast cancer, resistance to these drugs is the major cause of breast cancer mortality.

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Sydney : Researchers have found new evidence about the positive role of androgens, commonly thought of as male sex hormones but also found at lower levels in women, in breast cancer treatment.

In normal breast development, estrogen stimulates and androgen inhibits growth at puberty and throughout adult life.

Abnormal estrogen activity is responsible for the majority of breast cancers, but the role of androgen activity in this disease has been controversial.

The new research published in the journal Nature Medicine showed that androgens have potential for treatment of estrogen receptor positive breast cancer.

A cancer is called estrogen receptor positive if it has receptors for estrogen, according to Breastcancer.org.

Using cell-line and patient-derived models, the global team, including researchers at the University of Adelaide and the Garvan Institute of Medical Research in Australia, demonstrated that androgen receptor activation by natural androgen or a new androgenic drug had potent anti-tumour activity in all estrogen receptor positive breast cancers, even those resistant to current standard-of-care treatments.

In contrast, androgen receptor inhibitors had no effect.

“This work has immediate implications for women with metastatic estrogen receptor positive breast cancer, including those resistant to current forms of endocrine therapy,” said lead researcher Theresa Hickey, Associate Professor at the University of Adelaide.

“We provide compelling new experimental evidence that androgen receptor stimulating drugs can be more effective than existing (e.g. Tamoxifen) or new (e.g. Palbociclib) standard-of-care treatments and, in the case of the latter, can be combined to enhance growth inhibition,” said Wayne Tilley, Director of the Dame Roma Mitchell Cancer Research Laboratories, Adelaide Medical School, University of Adelaide.

Androgens were historically used to treat breast cancer, but knowledge of hormone receptors in breast tissue was rudimentary at the time and the treatment’s efficacy misunderstood.

Androgen therapy was discontinued due to virilising side effects and the advent of anti-estrogenic endocrine therapies.

While endocrine therapy is standard-of-care for estrogen receptor positive breast cancer, resistance to these drugs is the major cause of breast cancer mortality.

“The new insights from this study should clarify the widespread confusion over the role of the androgen receptor in estrogen receptor driven breast cancer,” said Elgene Lim, a breast oncologist and Head of the Connie Johnson Breast Cancer Research Lab at the Garvan Institute.

“Given the efficacy of this treatment strategy at multiple stages of disease in our study, we hope to translate these findings into clinical trials as a new class of endocrine therapy for breast cancer.”

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Azim Premji and Dr Devi Shetty chosen for PCB awards

Besides them 25 senior journalists have been selected for the ‘Press Club Annual Awards’, a release said.

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Bengaluru, Jan 19: The chairman of Wipro Limited Azim Premji and the founder chairman of Narayana Health Dr Devi Prasad Shetty are among those who have been selected for the annual awards given by the Press Club of Bangalore.

Premji has been chosen for ‘Press Club Person of the Year’, while Dr Shetty and actor-Director Sudeep Sanjeev have been selected for the ‘Press Club Special Award.’

Besides them 25 senior journalists have been selected for the ‘Press Club Annual Awards’, a release said.

Chief Minister B S Yediyurappa will facilitate the awardees at a function scheduled for the third week of February, it said.

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Elizabeth Olsen: Nepotism creates fear that you don’t deserve the work you get

The actress added that she “always had this need to prove myself to everyone around me that I work really hard”, adding: “I couldn’t walk in a room without everyone already having an opinion.”

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Elizabeth Olsen

Los Angeles, Jan 19 : Hollywood star Elizabeth Olsen says she once thought of changing her surname and distance herself from the success of her family because it was insanity growing up in the spotlight.

“It was insanity. There were times when my sisters would always be spotted and I would be in the car with them and it would really freak me out. It has helped me navigate how I want to approach my career,” said the actress, whose older sisters are Mary-Kate Olsen and Ashley Olsen.

The actress added that she “always had this need to prove myself to everyone around me that I work really hard”, adding: “I couldn’t walk in a room without everyone already having an opinion.”

Elizabeth opened up om the fears of nepotism.

“The thing about nepotism is the fear that you don’t earn or deserve the work. There was even a part of me when I was a little girl that thought if I’m gonna be an actress I’m going to go by Elizabeth Chase, which is my middle name. And then, once I started working, I was like, ‘I love my family, I like my name, I love my sisters. Why would I be so ashamed of that?’ It’s fine now,” she said.

The actress said fame has made her more of a homebody.

“Fame has also made me someone who is more of a homebody than maybe I would like to be but I know where not to go. If I could do whatever I wanted for the day, I’d start with the gym, then I’d go to the grocery store, because it’s my favourite thing,” Elizabeth told The Sun.

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