Connect with us

Health

Fish oil reduces bleeding risk in surgery patients: Study

Published

on

fish oil

New York, Dec 5: Fish oil, containing the omega-3s, lowers the risk of bleeding during surgery, say, researchers, challenging current recommendations to stop fish oil.

Fish oil is among the most common natural supplement for treatment of hypertriglyceridemia or prevention of cardiovascular disease.

However, concerns about theoretical bleeding risk have led to recommendations that patients should stop taking fish oil before surgery or delay in elective procedures for patients taking fish oil by some healthcare professionals.

The study, published in the journal Circulation, found that higher blood omega-3 levels — eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) — were associated with lower risk of bleeding.

For the study, 1,516 patients scheduled for cardiac surgery were randomised to omega-3s or placebo.

The dose was 6.5-8 grams of EPA+DHA over two-five days before surgery, and then 1.7 grams per day beginning the morning of surgery and continuing until discharge.

The findings showed that there was a significant reduction in the number of units of blood needed for transfusions.

In another analysis, the higher the blood EPA+DHA level on the morning of surgery, the lower the risk for bleeding, according to the Bleeding Academic Research Consortium (BARC) criteria.

“The researchers in this study concluded that these findings support the need to reconsider current recommendations to stop fish oil or delay procedures for people on fish oil before cardiac surgery,” said Bill Harris, Founder of OmegaQuant.

While Omega-3s, specifically EPA and DHA, are important for heart, brain, eye and joint health, most people do not get enough of these valuable fatty acids, which can increase their risk of the most serious health issues.

IANS

Blog

India witnesses significant rise in dementia-related cases: Lancet

The results showed that the number of deaths from dementia has increased by 148 per cent over the same 26-year period.

Published

on

Alzheimer

Moscow, Dec 12 : With number of individuals living with dementia increasing globally owing to ageing population, a Lancet study on Wednesday revealed that India witnessed a significant growth in the number of Alzheimer’s disease and other cases of dementia from 1990 till 2016.

According to the report published in Lancet Neurology journal, India witnessed nearly 2.9 million cases of Alzheimer’s disease and other cases of dementia in the 26-year period and nearly 1.4 lakh deaths arising from the problem.

The results showed that the number of people suffering from Alzheimer’s and other dementia increased from 20.2 million in 1990 to 43.8 million globally in 2016.

Of these, 27 million were women and 16.8 million were men.

To reach this conclusion, an international group of collaborating scientists, including HSE Professor Vasily Vlasov, analysed data from 195 countries on the spread of Alzheimer’s disease and other dementia between 1990 and 2016.

The results showed that the number of deaths from dementia has increased by 148 per cent over the same 26-year period.

Dementia is now the fifth most common cause of death worldwide and the second most common — after coronary heart disease — among people aged 70 or older, said the report.

Vlasov noted that according to the data, more than 1 million Russians — most over 50 — were suffering from dementia in 2016.

Researchers have linked high BMI, smoking (including all smoked tobacco products), and diet high in sugar-sweetened beverages as risk factors for dementia.

Although differences in coding for causes of death and the heterogeneity in case-ascertainment methods constitute major challenges to the estimation of the burden of dementia, future analyses should improve on the methods for the correction of these biases, said the study.

“Until breakthroughs are made in prevention or curative treatment, dementia will constitute an increasing challenge to health-care systems worldwide,” it added.

There is growing evidence of risk factors for dementia, which shows that lifestyle and other interventions might, if implemented effectively, contribute to delaying the onset and reducing the future number of people who have dementia.

Continue Reading

Health

Late childbirth linked to high breast cancer risk

Published

on

Pregnant_Woman
Representative Image

New York, Dec 11: Women who had their first child after 35 may be at an increased risk of developing breast cancer than their peers who do not have children, according to a study contrary to conventional wisdom that childbirth is protective against breast cancer.

Besides late childbirth, women who had a family history of breast cancer or who had a greater number of births also had an increased risk for breast cancer after childbirth. The pattern looked the same whether or not women breastfed.

While the risk was higher for women who were older at first birth, there was no increased risk of breast cancer after a recent birth for women who had their first child before 25, said researchers from the University of North Carolina (UNC) in the US.

“This is evidence of the fact that just as breast cancer risk factors for young women can differ from risk factors in older women, there are different types of breast cancer, and the risk factors for developing one type versus another can differ,” said Hazel B. Nichols, Professor at the UNC.

Although childbirth is still protective against breast cancer, researchers say it can take more than two decades for benefits to emerge.

Breast cancer is more common in older women, with the median age of 62 at diagnosis. But, the study, published in the Annals of Internal Medicine, identified elevated breast cancer risk after childbirth in women younger than 55.

In women 55 years and younger, breast cancer risk peaked about five years after they gave birth, with risk for mothers 80 per cent higher compared with women who did not gave birth.

Twenty-three years after giving birth, women saw their risk level off, and pregnancy started to become protective.

For their analysis, the team pooled data from 15 prospective studies from around the globe that included 889,944 women. In addition to looking at breast cancer risk after childbirth, they also evaluated the impact of other factors such as breastfeeding and a family history of breast cancer.

The findings could be used to develop better breast cancer risk prediction models to help inform screening decisions and prevention strategies, Nichols said.

IANS

Continue Reading

Health

Baby born from transplanted uterus from dead donor big breakthrough: Doctors

Published

on

transplanted uterus baby
Nearly a year after the birth, the mother and her baby daughter are both healthy. (Photo Credit- AP/Dr Wellington Andraus)

Brasilia/New Delhi, Dec 6: The world’s first baby born using a womb transplanted from a dead woman is a breakthrough in the field of obstetrics and a great advantage for women combating infertility, say Indian doctors.

According to a case study published in The Lancet on Wednesday, a healthy baby girl was born in 2017, following the uterus transplant from a 45-year-old brain-dead woman.

The womb transplant, lasting over 10 hours, took place in Sao Paolo in Brazil in September 2016. The baby was born in December 2017.

The uterus was removed from the donor and transplanted into the recipient in a surgery that also involved connecting the donor uterus and recipient’s veins and arteries, ligament and vaginal canals.

“It is a breakthrough in the field of obstetrics as well as a great advantage for women who lost their uterus for some reason or don’t have from birth. This would increase the availability of the uterus as living donors are always in scarcity,” Ranjana Sharma, Senior Consultant, (Obstetrics and Gynaecology), Indraprastha Apollo Hospitals, New Delhi, told IANS.

In a majority of such cases, the uterus does not survive after transplant in the recipient due to infections or rejection by the body’s immune system.

But in the case of a uterus transplant from a cadaver, the potential danger for infections is more, says Kamini A. Rao, Medical Director, Milann-The Fertility Centre, Bengaluru.

“One will never be able to find whether the dead woman has had any infections in the uterus, nor in the vaginal canals and whether it is treatable or not,” Rao told IANS.

“This is not in the case of a kidney or liver transplant, clearly because the vagina is an exposed area and since you are unable to identify what kind of organisms were growing, there is a potential danger for rejection,” Rao added.

Still, the advantage is that the surgery takes place only for a person. It is a very good thing compared to a live donor, she noted.

“When a transplant is dome from a live donor, there is a greater responsibility towards both the donor and recipient, but in a dead body the doctors can be a bit relaxed,” Sharma said.

Importantly, in the Lancet case study, the uterus had an interval of eight hours before getting connected to the living body.

“Up till now it was not known that uterus can survive more than four hours out of a living body, however, the present case shows that the uterus is a quite strong an organ,” Sharma said.

“Just as cornea, kidney, liver, heart, the pancreas, I am hopeful that the uterus will also be added in the gamut of organs taken out so that many more people will be benefited,” Rao noted.

Moreover, the doctors said that while a transplanted kidney or liver stays for life, it is not the case with the uterus.

“This is only to give birth to a child. Once the baby reaches maturity, the uterus is taken out along with the baby. It is because we don’t know the long-term effects of having a foreign uterus in the body. So far the uterus have not been left after taking out the baby. It is then discarded, like any hysterectomy,” Sharma said.

Besides women who lost uterus or do not have from birth, this kind of transplant could also some day open doors for people who are transgender, Sharma suggested.

“However sometimes you may only have an absent uterus like in this case. But for transgender, you will also have to take the donor eggs, like a surrogate gestation,” Rao pointed out.

IANS

Continue Reading
Advertisement

Most Popular