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Eating nuts may cut risk of colon cancer recurrence by half

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New York, May 19: Researchers have found that eating tree nuts which include almonds, walnuts, hazelnuts, cashews, and pecans, among others, is associated with significant reduced risk of colon cancer recurrence.

The observational study of 826 patients with stage III colon cancer showed that those who consumed two ounces or more of tree nuts per week had a 46 per cent lower chance of cancer recurrence and 53 per cent lower chance of death than those who did not.

Researchers were particularly interested in nut consumption because it has been linked to lower incidence of obesity, Type-2 diabetes, and reduction in insulin resistance.

These health conditions represent a state of excess energy and are each associated with a higher risk of recurrence and death from colon cancer.

“Numerous studies in the fields of heart disease and diabetes have shown the benefits of nut consumption, and we felt that it was important to determine if these benefits could also apply to colorectal cancer patients,” said lead study author Temidayo Fadelu, a clinical fellow in medicine at Dana Farber Cancer Institute in Boston, Massachusetts, US.

“Patients with advanced disease who benefit from chemotherapy frequently ask what else they can do to reduce their chances of recurrence or death, and our study is an important contribution to the idea that modifying diet and physical activity can be beneficial,” Fadelu said.

The findings are scheduled to be presented at the upcoming 2017 American Society of Clinical Oncology (ASCO) annual meeting in Chicago from June 2-6.

There was no associated reduction in cancer recurrence and death among patients who consumed peanuts or peanut butter.

The reason may be that, being legumes, peanuts have a different metabolic composition than tree nuts, according to the study authors.

In their next step, the researchers hope to conduct a randomised, controlled clinical trial where diet recommendations are given at the start of the study to prove that tree nuts can reduce recurrence and death after treatment for colon cancer.

“We need to look at the potential positive impact of nut consumption on survival at other stages of colon cancer, particularly stage IV. Ultimately, we need to understand how nuts confer this protective effect,” Fadelu said.

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Can drinking too much water harm you?

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Toronto, May 23: Do you drink too much water? Beware, overhydration — excess fluid accumulation — can lead to dangerously low sodium levels or in the blood or result in brain swelling, researchers say.

Hyponatremia, a life-threatening condition of brain swelling, is more common in elderly patients and can cause cognitive problems and seizures.

“(Hyponatremia) occurs in common pathological conditions, including brain injury, sepsis, cardiac failure and in the use of drugs, such as MDMA (ecstasy),” said Charles Bourque from the McGill University in Canada.

While it was yet uncertain how hyponatremia develops, the study found that a defect in the hydration sensing mechanism of the brain could be the culprit.

The researchers said that brain’s hydration sensing neurons could not detect overhydration in the same way that they detect dehydration.

Overhydration activates Trpv4 — a calcium channel that can be found in glial cells, that act to surround hydration sensing neurons.

It is cellular gatekeeper implicated in maintaining the balance of water in the body.

“Our study shows that it is in fact glial cells that first detect the overhydrated state and then transfer this information to turn off the electrical activity of the [hydration sensing] neurons,” Bourque explained.

“Our specific data will be important for people studying hydromineral and fluid electrolyte homeostasis, and clinicians who treat patients faced with hyponatremia,” he noted.

The results, published in the journal Cell Reports, showed that overhydration is first identified by the Trpv4 channel which triggers the release of a type of amino acid known, taurine, which acts as a trip wire to inhibit hydration sensing neurons.

“Preclinical models of hyponatremia will be used to examine if the mechanism we report is affected in this condition with the long-term objective of designing new treatments or diagnostic tools,” Bourque added.

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An egg a day may keep heart diseases away

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Beijing, May 22: If you thought eating eggs is bad for your heart due to their high cholesterol content, think again. A large study has now shown that people who consume an egg every day could significantly reduce their risk of cardiovascular diseases.

“The present study finds that there is an association between moderate level of egg consumption (up to one egg/day) and a lower cardiac event rate,” the study authors said.

The researchers pointed out that eggs are a prominent source of dietary cholesterol, but they also contain high-quality protein, many vitamins and bioactive components such as phospholipids and carotenoids.

Cardiovascular disease (CVD) is the leading cause of death and disability worldwide mostly due to ischaemic heart disease and stroke (including both haemorrhagic and ischaemic stroke).

For the study, published in the journal Heart, Chenxi Qin from Peking University Health Science Centre in Beijing, and colleagues set out to examine the associations between egg consumption and cardiovascular disease, ischaemic heart disease, major coronary events, haemorrhagic stroke and ischaemic stroke.

They used data from the China Kadoorie Biobank (CKB) study, an ongoing prospective study of around half a million (512,891) adults aged 30 to 79 from 10 different geographical areas in China.

The researchers focused on 416,213 participants who were free of prior cancer, cardiovascular disease (CVD) and diabetes.

Analysis of the results showed that compared with people not consuming eggs, daily egg consumption was associated with a lower risk of CVD overall.

In particular, daily egg consumers (up to one egg per day) had a 26 per cent lower risk of haemorrhagic stroke, a 28 per cent lower risk of haemorrhagic stroke death and an 18 per cent lower risk of CVD death.

In addition, there was a 12 per cent reduction in risk of ischaemic heart disease observed for people consuming eggs daily, when compared with the ‘never/rarely’ consumption category — about 2.03 eggs per week.

This was an observational study, so no firm conclusions can be drawn about cause and effect, but the authors said their study had a large sample size and took into account established and potential risk factors for CVD.

IANS

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Delhi govt planning free dialysis at pvt hospitals: Jain

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New Delhi, May 21 : The Delhi government is planning to make the dialysis procedure free at private hospitals and dialysis centres on a public-private-partnership basis, subject to conditions, Health Minister Satyendar Jain said today.

Jain said only those private hospitals and standalone centres which have more than 10 dialysis machines and are empanelled under the Delhi Government Employees Health Scheme or the Central Government Health Scheme would be eligible to become a partner in the project.

Delhi government through the Delhi Arogya Kosh will pay them Rs 1,274 per dialysis.

Delhi residents who have been living in the city for the past three years and having an annual income of less than Rs 3 lakh shall be eligible to avail the facility, Jain said.

The government is also installing dialysis machines at its own hospitals.

“We have installed 15 machines out of the 75 machines that we intend to install at various hospitals,” he said.

Jain said the idea behind providing the facility at private hospitals or dialysis centres is to cut the travel time for patients, who otherwise may have to go long distance to avail that facility at a government hospital.

“This would be like a reverse referral facility where patients would be referred to an empanelled hospital or centre nearby their home,” he said.

Jain said the government was in an “expansion mode” as far as health services were concerned.

“Five of our hospitals have already earned NABH entry-level accreditation – Pt Madan Mohan Malviya Hospital, Shri Dada Dev Matri Avum Shishu Chikitsalaya, Acharya Shree Bhikshu Hospital, Guru Gobind Singh Hospital and Dr Baba Saheb Ambedkar Hospital,” he said.

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